![]() ![]() What are the clinical features of drug-induced hyperhidrosis? Withdrawal from non-prescription drugs such as alcohol and caffeine can also cause generalised hyperhidrosis. Diabetic medications such as glipizide and insulin.Medications that can affect endocrine function and thus cause hyperhidrosis can include: Medications that affect endocrine function Quinolone antibiotics (eg, ciprofloxacin).Cephalosporins (eg, ceftriaxone or cefuroxime). ![]() Non-steroidal anti- inflammatory medications ( NSAIDs), such as celecoxib and naproxen.Īntimicrobial medications and antibiotics that can cause hyperhidrosis include:.Opioids, such as morphine, oxycodone, fentanyl, and tramadol.Pain relief medications that can cause hyperhidrosis include: These increase sweating through direct stimulation of receptors in sweat glands.Acetylcholinesterase inhibitors, such as donepezil or benztropine.Medications used to treat dementia or Parkinson disease include: Medications to treat dementia or Parkinson disease Antipsychotics, such as haloperidol and clozapine.Tricyclic antidepressants, such as amitriptyline.Selective serotonin reuptake inhibitors (SSRIs), such as citalopram.Medications used to treat psychiatric conditions that can cause hyperhidrosis include: Medications to treat psychiatric conditions ĭifferent classes of medications can influence the sweating response by acting centrally in the brain and the peripheral nervous system. Other factors that can contribute to increased sweating include a family history of increased sweating, and underlying medical conditions such as obesity, diabetes, hyperthyroidism, menopause, or cancer. It can begin at any age, and affect people of all races. There are no specific characteristics that increase the risk of a person getting drug-induced hyperhidrosis. Due to impaired negative feedback to the hypothalamus, acetylcholine causes the body to sweat more than is needed for core temperature to reach homeostasis. Īcetylcholine exerts its effect via receptors found on sweat glands. ![]() It results from the release of acetylcholine by medications that block the action of acetylcholinesterase, an enzyme that breaks down the neurotransmitter. D rugs can act on the hypothalamus or at spinal thermoregulatory centres, at sympathetic ganglia or at the eccrine-neuroeffector junction. What leads to drug-induced hyperhidrosis?ĭrug-induced hyperhidrosis is the most common cause of secondary hyperhidrosis. ![]()
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